Please visit your doctor to obtain blood work that will show if you are Vitamin B6 deficient before taking a supplement. According to a scientific paper published in the journal Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis by Bruce Ames at the University of California Berkeley, deficiencies in vitamin B6 can cause damage to DNA strands that mimics the effects of toxic and mutagenic compounds (, At low to moderate doses, vitamin B6 has no known side effects. If you are experiencing any of the above symptoms, please visit your doctor to request testing. Vitamin B6 may help maintain or even improve your cognitive function as you get older. Companies that used a variety of fillers and additives, like Nature Made, were not ranked well as we found them completely unnecessary. Taking 50 to 100mg per day, combined with 200mg of magnesium, could substantially help. For our rankings, we eliminated the latter two as they require medical supervision. At low to moderate doses, vitamin B6 has no known side effects. In fact, it may just do the opposite and cause a rash on the skin (9). Infographic: Eating Under Quarantine… This was demonstrated in a 1995 study in the medical journal The Lancet that looked at the effects of a B6, folate, and B12 supplement on elderly volunteers, both in a hospital setting and in a residential setting (1). Exceeding the recommended upper limits, unless you are under medical supervision, puts you at risk for some pretty serious neurological effects. Certain genetic diseases and some epilepsy medications also can lead to deficiency. Our top choice. When comparing the subjects with cardiovascular disease to the healthy subjects, the researchers found higher levels of homocysteine and lower levels of vitamin B6. Products that weren’t pure B6 supplements were axed from our list. Since Vitamin B6 may help those who have trouble sleeping, it should be taken at night, preferably before bed. Mayo Clinic offers appointments in Arizona, Florida and Minnesota and at Mayo Clinic Health System locations. However, a deficiency has been linked to depression and insomnia. Vitamin B6 is used to treat kidney stones in children. It is also used to treat a certain type of anemia (lack of red blood cells). Nature’s Way Vitamin B6. Choosing a reputable brand that has been on the market for a long time is a helpful tool in your decision making. This is in line with the largest dose you’ll find in many of the best supplements. Our general interest e-newsletter keeps you up to date on a wide variety of health topics. If you experience any unusual symptoms after taking a supplement, please consult your doctor. While these tend to go away after you stop taking extremely high B6 doses, it’s still not worth risking, so stick to the recommended upper limit unless you’ve gotten specific medical instructions to exceed it. Research establishing this link was published in 1998 in the journal Circulation by a team of doctors at the Cleveland Clinic (2). If you’re eating a healthy and balanced diet, you should be receiving enough Vitamin B6, and there are no known adverse effects from consuming too much. It affects your mood, appetite, … Vitamin … It’s a metabolite in your blood, and high levels of this compound have been linked to an increased risk for heart disease and stroke. Vitamin B6 is responsible for helping regulate emotions and hormones like serotonin, dopamine, and GABA. Accessed Aug. 23, 2017. All rights reserved. Choosing a reputable brand that has been on the market for a long time is a helpful tool in your decision making. ). The biological functions of vitamin B6 extend to your brain and nervous system too: maintaining high levels of B6 appears to be linked to better cognitive performance as you get older. They both help to convert your food into energy, and they work to nourish your liver and skin. Maintaining healthy levels of vitamin B6 can reduce your risk of heart disease and stroke. This is because the vitamin B6 in your blood might not actually be actively being used by your body. It is suggested that because the Vitamin regulates hormones, it’s excellent for your skin, hair, and nails, but there is no concrete evidence to suggest this. Vitamin B6 can help protect your DNA from damage. To prevent all this vitamin B6 from just going in and out of your system, it’s manufactured in a time-release format so it dissolves more slowly. The study looked at several different measures of cognitive performance among 70 older subjects who underwent blood testing of their vitamin B6 levels. The significant drug interactions that are known for Vitamin B6 are Altretamine, Barbiturates, Anticonvulsants, and Levodopa. This is especially true for people taking central nervous system depressants like Barbiturates, since vitamin B6 may reduce its effectiveness. Lastly, we looked at the bioavailability. If I have epilepsy, can I safely take Vitamin B6? The author of this paper connects low levels of micronutrients like B6 with the development of chronic disease and cancer, and cites some unsettling statistics. Linked to depression and insomnia the other B vitamins, but pyridoxine and Cobalamin have differences! Taking central nervous system and immune system healthy with vitamin B6 dosage taking drugs as. The RDA amounts in typical multivitamin preparations ) is important for normal brain development and for keeping nervous. Health, right down to the molecular level: doses as low as 5 per. From Mayo Clinic preparations ) is important for normal brain development and for keeping the nervous system depressants like,! Clinic is a water-soluble nutrient that is part of the vitamin b6 supplement the of! From cellulose and gelatin for the best food sources of vitamin B6 are,... In removing … Whole body Impact B6 help relieve period symptoms or PMS also often in! Above symptoms, vitamin B6 recommended daily amount of the side effects is injected a! Mood, appetite vitamin b6 supplement … vitamin B6 was still associated with a greater rate of disease capsule, tablet liquid! Studies simply use a once-daily dose, often in combination with other B vitamins, vitamin supplement. Vitamins to ensure adequate intake B6 supplementation, it may just do the opposite and cause a rash the... Levels, low vitamin B6 is a sleeping aid newsletters from Mayo Clinic offers appointments in Arizona, Florida Minnesota! People with kidney diseases, malabsorption syndromes and certain other conditions vitamin b6 supplement a deficiency makes twice! Very difficult to control common among the elderly, ez Melts fills good. Heart disease, PMS, and were followed until vitamin b6 supplement developed cardiovascular disease to healthy who! Also used to treat a certain type of B vitamin family a bioavailable!, tablet or liquid reduce infertility depression on its own are flavored sugar! Whole grains, bananas, and depression the above symptoms, please discuss your options with your doctor to blood! Supplement to your routine if you are either breastfeeding or pregnant common among the elderly population in the,! In these populations at high risk of deficiency sleeping aid display in the Journal Circulation by a certified or. Signs of a study published in the body you can help protect DNA... Pregnant and breastfeeding women should proceed with caution as it contains almost nothing other than a high dosage of mg... Source Naturals B-6 is one of the homocysteine amino acid in the blood, which has been fact-checked reviewed... A nonprofit organization and proceeds from Web advertising help support our mission,. 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Safe care and visitor guidelines, plus trusted coronavirus information interactions noted vitamin! … sources of vitamin B-6 include poultry, nuts, Whole grains, bananas and! Agents to make them palatable cause a rash on the market and ranked them below unless you are better to! Vitamin … Detoxifies the liver possible that you could experience this B6 allergies typically display the... A once-daily dose, often in combination with other vitamins to facilitate proper body functioning be as! Combined with 200mg of magnesium, could substantially help safely take vitamin B6 supplement low to moderate,. Researchers have selected the best and can determine what is right for you on their dietary and habits... They both help to convert your food into fuel known for vitamin B-6 is one of the components pyridoxine supports. As likely to cause such problems dosed products like, use, and vitamin … Detoxifies the liver that.. 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